Funding

The MRCAS Lab has been consistently funded for the past 10+ years to conduct cutting edge research, including major randomized control trials.

Past and current funding has included support from the National Institutes of Health, Veterans Health Administration, and industry.

Ongoing Research Support

NSF-SCH 2310187

An AI Coach for Enhancing Teamwork in the Cardiac Operating Room

Role: Principal Investigator

Dates: 2022-2026

Description: The goal of this multi-disciplinary project is to develop an intelligent agent – referred to as the “AI Coach” – that enhances surgical teamwork by monitoring and assessing the collaborative performance of surgical teams using multimodal sensor hardware and transformative data-driven algorithms, as well as by providing human-interpretable and usable feedback to the members of surgical teams for enhancing teamwork and reducing preventable errors through an intelligent user interface.

NIH-NHLBI R01HL157457 (MPI: Dias/Gombolay)

A Robot-Assisted Perfusion System to Improve Patient Safety in the Cardiac Operating Room

Role: PI of Harvard Subcontract (2022-2025), Principal Investigator (2021-2022)

Description: The goal of this project is to develop a system that will learn from expert perfusionists in the cardiac operating room and will be integrated into the surgical workflow as an artificial intelligence teammate. This clinical decision support system will support perfusionists during critical decision-making and will be used to standardize gold standard patient care, mitigating errors, and preventing patient harm. 

NIH-NHLBI R01HL126896

A Novel Cognition-Based Guidance System to Improve Surgical Safety

Role: Principal Investigator

Dates: 2020-2025

Description: The goal of this project is to develop novel approaches to using process and patient real-time data, and device status information dynamically and proactively to provide guidance forward from the current surgical state. We will develop and test intraoperatively a Cognition-based Guidance System which will support individual and team interactions via dynamically updated electronic guidance that are responsive to the details of the on-going process (i.e., context-aware), to the patient’s current medical condition (i.e., patient-aware), and to cognitive workload demands on the participating clinicians (i.e., workload-aware).

Completed Research Support

NIH-NHLBI R01HL126896

Developing Standardized Intraoperative Process Models to Enhance Surgical Safety

Role: Principal Investigator

Dates: 2016-2019

Description: The rates of preventable harm to patients in the U.S. are at concerning levels. The operating room is the most common site for adverse events in the hospital. To enhance surgical patient safety we introduce a novel approach that leverages advances in information technology. We propose to develop and analyze innovative surgical process models to facilitate standardization of critical procedural steps in cardiac surgery ("smart checklists"). We have assembled an experienced multidisciplinary team and we anticipate that our novel approach will contribute to a transformational redesign toward a health system that is waste-free, harm-free and highly reliable.

NIH-NHLBI R01HL078839 Riviere (MPI) Zenati (MPI)

Robotic Crawler for Epicardial Interventions

Role: Principal Investigator

Dates: 2004-2016

Description: The major goal of this grant is to develop a semi-autonomous epicardial crawling robot (Heartlander) to enable image-guided minimally invasive treatment of heart failure.

Seventh Framework Programme of the European Community (FP7) Fiorini (PI)

Safety of Robotic Surgery (SAFROS)

Role: Investigator

Dates: 2011-2016

Description: The goal of this multicenter European and North American consortium is to apply cognitive science approach to improve safety of robotic surgery.

NIH-NHLBI R01HL079940

Articulated Robot for Epicardial Interventions.

Role: Principal Investigator

Dates: 2006-2015

Description: This project focuses on the development and evaluation of an innovative approach for performing minimally invasive cardiac surgery (MICS) based on a highly articulated robotic probe (HARP).

Heinz Foundation/MERITS

Snake Robot for Intrapericardial Navigation

Role: Principal Investigator (Investigator-initiated)

Dates: 2003-2004

Description: The major goal of this study was to develop a prototype medical snake robot for intrapericardial navigation around the beating heart.

The Pittsburgh Foundation

Docking Minimally Invasive Tools to the Beating Heart

Role: Principal Investigator (Investigator-initiated)

Dates: 2002-2004

Description: The major goal of this study was to develop new approaches to robotic beating heart surgery using an organ-mounted system.

Ravitch/Hirsch Center for Minimally Invasive Surgery, University of Pittsburgh

Use of Thoracoscopic Surgery using the ZEUS robotic system (Robotically Assisted Instrumentation and Visualization) in a Porcine Preparation

Role: Principal Investigator (Investigator-initiated)

Dates: 2000-2001

Description: The major goal of this study was to establish a minimally invasive model for training in robotic surgery in a porcine preparation.

Computer Motion Inc./FDA IDE G980253

Clinical Investigation for the use of the ZEUS robotic surgical system for Coronary Artery Bypass Grafting (CABG)

Role: Principal Investigator

Dates: 2000-2001

Description: The major goal of this FDA-sponsored study was to evaluate the ZEUS robotic Teleoperated surgical system for construction of the left internal mammary artery anastomosis to the left anterior descending coronary artery in humans.